Difference between Prokaryotic and Eukaryotic cells

Prokaryotic cells


Nucleus: no distinct nucleus

Chromatin material;The genetic material (DNA) is without any nuclear membrane and freely present in the cytoplasm.

Chromosome; Chromosome is formed of DNA only.

Organelles; Few organelles, None are surrounded by an envelope (two membranes) internal membrane scarce if present usually associated with respiration or photosynthesis.

Ribosomes; Ribosomes are 70 S smaller subunit is 30S while larger subunit is 50 S.

Cell wall; Cell wall is composed of peptidoglycan or murein. When polysaccharide chains are bound covalently to shorter chains of amino acids. Peptidoglycan is formed. The entire cell wall is considered as a single complex molecule called sacculus.

Cell division In prokaryotes mitosis is missing and the cell divided by binary fission.

Organisms; Organisms possessing prokaryotic cells are called prokaryotes

Origin/Evaluation; Prokaryotes are present primitive stage of evaluation.

Flagella; Simple, lacking microtubules extracellular (not enclosed by cell surface membrane) 20 nm diameter.

Respiration; Mesosomes in bacteria except cytoplasmic membrane in blue green algae.

Photosynthesis; No chloroplasts no membrane stacking

Nitrogen fixation; some bacteria 

Form; Mainly unicellular

Cell size; Average diameter 0.5 – 20 µm

Examples; Prokaryotes include bacteria and blue green algae (cyanobacteria).


Eukaryotic cells 


Nucleus: True nucleus 

Chromatin material; A nucleus is present in which nuclear material (chromosomes) is enclosed in double nuclear membrane.

Chromosome; Chromosome is formed of DNA and protein.

Organelles; Many organelles envelop-bound organelles present e.g. nucleus, mitochondria, and chloroplasts. Great diversity of organelles bounded by single membrane e.g. lysosomes, vacuoles, micro bodies, endoplasmic, reticulum etc.

Ribosomes; Ribosomes are 80 S smaller subunit is 40 S while larger subunit is 60 S.

Cell wall; The cell wall, if present is formed of cellulose in most of the plant cells and is formed of chitin in fungi.

Cell division; Cell division by mitosis.

Organisms; Organism possessing eukaryotic cells is called eukaryotes.

Origin/Evaluation; Eukaryotes probably evolved from prokaryotes.

Flagella; Complex structures, with 9 + 2 arrangement of microtubules intracellular (surrounded by cell surface membrane) 200 nm diameter

Respiration; Mitochondria for aerobic respiration.

Photosynthesis; Chloroplasts containing membranes which are usually stacked into lamellae or grana.

Nitrogen fixation; Mainly have the ability.

Form; Mainly multi-cellular (except prototista, many of which are unicellular

Cell size; 10-100 µm diameter common commonly 1000-10000 times volume of prokaryotic cells.

Examples; Eukaryotes include all other unicellular or multi-cellular organisms such as animals, plants fungi and protista.





Bio learning

It's Ali Anwar here, graduated from SINDH university Jamshoro Pakistan and working in health department

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